Anurag S. Rathore, Garima Thakur, Nikita Saxena, “System and method to control a continuous biopharmaceutical manufacturing”, application 202121004083 filed on 29th January 2021 at the Indian Patent Office.
Anurag S. Rathore, Garima Thakur, Nikita Saxena, “Surge tank based system for automated operation and control of continuous biopharmaceutical manufacturing”, application 202011034558 filed on 11th August 2020 at the Indian Patent Office.
Anurag S. Rathore, Garima Thakur, Vishwanath Hebbi, Tushar Savane, “A system for real time monitoring of protein and excipients”, application 202011007820 filed on 24th February 2020 at the Indian Patent Office. PCT/IN2021/050176 filed on 24 February 2021.
Anurag S. Rathore, Purva Bhojane, Md. Areeb Afzal, “Fingerprinting Biotherapeutics with FTIR Spectroscopy'', Indian Patent Application 201911032987 filed on 30th August 2019 at the Indian Patent Office.
Anurag S. Rathore, Ashish Chauhan, S. Kathiresan, “Bioprocess Performance Enhancing Strains Of Escherichia Coli”, Indian Patent Application No. 201911033511 dated August 20, 2019.
Anurag S. Rathore, Nikhil Kateja, Nitika Singh “A process for preparation of pegylated therapeutic proteins'', Indian Patent Application 201911049731 filed at the Indian Patent Office. PCT/IN2020/050999 filed December 3, 2020.
Anurag S. Rathore, Garima Thakur, Vishwanath Hebbi, “A system for monitoring and control of chromatography”, application IN100482 filed on 28th March 2019 at the Indian Patent Office, PCT/IN2020/050264 filed on March 20, 2020, Publication number WO 2020/053875 on March 19, 2020.
Anurag S. Rathore, Claire Komives, Vishwanath Hebbi, S. Kathiresan, “Process for producing recombinant peptides”, application PD028671IN filed on 14th September 2018 at the Indian Patent Office. PD028671PCT filed on 24th June 2019.
Gaurav Goel, Anurag S. Rathore, Avinash Mishra, Rohit Bansal, “Polypeptide sequence and composition thereof”, Disclosure 201711030494 filed on 28 September 2017 the Indian Patent Office.
A. Rathore, V. Haridas, R. Bansal, Soumili Chattopadhyay, Sameer Dhawan, “A formulation for stabilizing biotherapeutics”, PD022345IN filed on 9th December 2016, PD022345PCT filed on 8th June 2017.
Anurag S. Rathore, Mili Pathak, Viki Chopda, “Method for monitoring of foulants present on chromatographic resins using fluorescence probe”, Patent Application No. 201611015421, filed June 7, 2016 at the Indian Patent Office, Date of Grant: 23 January 2020, Patent number: 330088. PCT/IN2017/050035 filed 12th July 2018. US Patent App. 16/069,745.
Anurag S. Rathore, Claire Komives, “Scaleable, low cost method of making snake antivenom peptide(s) and uses thereof”, application 778/DEL/2015, filed 20th March 2015 at the Indian Patent Office. Patent 341561 granted on 14th July 2020.
Anurag S. Rathore, K. D. P. Nigam, Mili Pathak, Harshit Agarwal, Abhishek Kumar Sharma, Nikhil Kateja, Vishwanath Hebbi, “An innovative coiled flow inverted reactor for continuous refolding of denatured recombinant proteins”, application 185/DEL/2015 filed 21st January 2015 at the Indian Patent Office, PCT/IN2016/000022 filed 20th January 2016.
Darpan Gupta, Rahul Bhambure, Rohit Sharma, Anurag S. Rathore“A process for purification of recombinant granulocyte colony stimulating factor”, Application 1880/DEL/2012, filed 19th June 2012 at the Indian Patent Office. PCT application 13/921891 filed 19th June 2013 at US Patent Office, Patent number 9422354.
Anurag S. Rathore, Stephen B. Lyle, David E. Steinmeyer, Scott I. Allen, John Meyer, Denis M. Boyle, John J. Buckley, Gary V. Johnson, “Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof”, application #20040048315, filed 26th August 2003, granted 3rd April 2012, Patent number 8148331.
Denis M. Boyle, John J. Buckley, Gary V. Johnson, David E. Steinmeyer, Michele Toal, Serdar Aykent, Anurag S. Rathore, “Methods for decreasing aggregate levels of pegylated growth hormone antagonists”, filed Sep 22nd 2003, granted 30 December 2008, Patent number US7470779B2
TECHNOLOGIES DEVELOPED:
An innovative coiled flow inverted reactor for continuous refolding of denatured recombinant proteins (patent application filed for US and for India)
Creation of a novel aqueous two phase extraction process for purification of biotech therapeutics (patent application filed for US and for India)
Creation of a novel single step process for purification of biotech therapeutics (patent application filed for US and for India)
CFD modeling of a helical coil heat exchanger to aid in scaleup from lab to manufacturing scale for Ranbaxy laboratories
Creation of a high throughput process development (HTPD) protocol for development of biotech processes for GE Healthcare
Proposed a novel approach for using multivariate data analysis (MVDA) for evaluating comparability of biotech processes and products for Dr Reddy Laboratories
Developed a process analytical technology (PAT) based control scheme for a process chromatography column for Biocon Ltd.
Creation of manufacturing process for Granulocyte Colony Stimulating Factor (GCSF), a biotech therapeutic - in negotiation with Indian biotech companies for licensing
